Difference between revisions of "RecU"

From SubtiWiki
Jump to: navigation, search
Line 69: Line 69:
  
 
* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** binds Holliday junctions with high affinity {{PubMed|24770420}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
Line 89: Line 90:
 
** form dimers {{PubMed|21600217}}
 
** form dimers {{PubMed|21600217}}
 
** [[RecA]]-[[RecU]] {{PubMed|16024744}}
 
** [[RecA]]-[[RecU]] {{PubMed|16024744}}
** [[RecU]]-[[RuvB]] {{PubMed|21600217}}
+
** [[RecU]]-[[RuvB]] {{PubMed|24770420,21600217}}
 +
** formation of a ternary complex [[RecU]]-[[RuvB]]-Holliday junction DNA {{PubMed|24770420}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''

Revision as of 10:30, 5 May 2014

  • Description: Holliday junction resolvase, DNA repair, homologous recombination and chromosome segregation; recognizes, distorts, and cleaves four-stranded recombination intermediates and modulates RecA activities, equivalent to E. coli RecU

Gene name recU
Synonyms recG, prfA, yppB, jopB
Essential no
Product Holliday junction resolvase
Function DNA repair/ recombination and chromosome segregation
Gene expression levels in SubtiExpress: recU
Interactions involving this protein in SubtInteract: RecU
MW, pI 23 kDa, 9.511
Gene length, protein length 618 bp, 206 aa
Immediate neighbours yppC, ponA
Sequences Protein DNA DNA_with_flanks
Genetic context
RecU context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RecU expression.png
















Categories containing this gene/protein

DNA repair/ recombination, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

  • Locus tag: BSU22310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • binds Holliday junctions with high affinity PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications

RecU in other organisms