Difference between revisions of "RuvA"
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * the inactivations of ''[[recU]]'' and ''[[ruvA]]-[[ruvB]]'' are synthetically lethal {{PubMed|24770420}} | ||
=== Database entries === | === Database entries === | ||
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
Revision as of 10:27, 5 May 2014
| Gene name | ruvA |
| Synonyms | |
| Essential | no |
| Product | Holliday junction DNA helicase |
| Function | DNA repair/ recombination |
| Gene expression levels in SubtiExpress: ruvA | |
| Interactions involving this protein in SubtInteract: RuvA | |
| MW, pI | 22 kDa, 5.384 |
| Gene length, protein length | 603 bp, 201 aa |
| Immediate neighbours | ruvB, bofC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27740
Phenotypes of a mutant
Database entries
- BsubCyc: BSU27740
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ruvA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU27740
- Structure:
- UniProt: O05392
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Justin S Lenhart, Jeremy W Schroeder, Brian W Walsh, Lyle A Simmons
DNA repair and genome maintenance in Bacillus subtilis.
Microbiol Mol Biol Rev: 2012, 76(3);530-64
[PubMed:22933559]
[WorldCat.org]
[DOI]
(I p)
S C West
Processing of recombination intermediates by the RuvABC proteins.
Annu Rev Genet: 1997, 31;213-44
[PubMed:9442895]
[WorldCat.org]
[DOI]
(P p)
Original publications
Cristina Cañas, Yuki Suzuki, Chiara Marchisone, Begoña Carrasco, Verónica Freire-Benéitez, Kunio Takeyasu, Juan C Alonso, Silvia Ayora
Interaction of branch migration translocases with the Holliday junction-resolving enzyme and their implications in Holliday junction resolution.
J Biol Chem: 2014, 289(25);17634-46
[PubMed:24770420]
[WorldCat.org]
[DOI]
(I p)
Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290]
[WorldCat.org]
[DOI]
(P p)
