Difference between revisions of "GlxA"
| Line 115: | Line 115: | ||
* '''Additional information:''' | * '''Additional information:''' | ||
** number of protein molecules per cell (minimal medium with glucose and ammonium): 229 {{PubMed|24696501}} | ** number of protein molecules per cell (minimal medium with glucose and ammonium): 229 {{PubMed|24696501}} | ||
| + | ** number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 3299 {{PubMed|21395229}} | ||
| + | ** number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 1387 {{PubMed|21395229}} | ||
| + | ** number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 2906 {{PubMed|21395229}} | ||
=Biological materials = | =Biological materials = | ||
| − | |||
* '''Mutant:''' | * '''Mutant:''' | ||
Revision as of 14:22, 17 April 2014
- Description: glyoxalase I
| Gene name | glxA |
| Synonyms | ipa-18r, ywbC |
| Essential | no |
| Product | glyoxalase I |
| Function | detoxification of methylglyoxal |
| Gene expression levels in SubtiExpress: glxA | |
| Metabolic function and regulation of this protein in SubtiPathways: glxA | |
| MW, pI | 14 kDa, 4.429 |
| Gene length, protein length | 378 bp, 126 aa |
| Immediate neighbours | ywbD, ywbB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38370
Phenotypes of a mutant
- increased sensitivity to methylglyoxal PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- methylglyoxal + BSH --> S-lactoyl-bacillithiol (BSH) PubMed
- Protein family: glyoxalase I family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P39586
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: glxA PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
- number of protein molecules per cell (minimal medium with glucose and ammonium): 229 PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 3299 PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 1387 PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 2906 PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
