panG

panG
168

ketopantoate reductase

Locus
BSU_14440
Molecular weight
33.42 kDa
Isoelectric point
6.14
Protein length
303 aaSequenceBlast
Gene length
912 bpSequenceBlast
Function
biosynthesis of coenzyme A
Product
ketopantoate reductase
Essential
no
E.C.
1.1.1.-
Synonyms
ykpB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1893 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,514,052  1,514,963
The protein
Catalyzed reaction/ biological activity
ketopantoate + H+ + NADPH --> (R)-pantoate + NADP+ PubMed
Protein family
ketopantoate reductase family (with PanE, according to UniProt)
Structure
3HN2 (PDB) (from Geobacter metallireducens, 26% identity)
O31717 (AlphaFold)
Expression and Regulation
Operons
Genes
ykpA-panG
Description
PubMed
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ykpA→panG

2025-03-17 04:18:15

Jstuelk

92

ce96627e6bc3eef0cadea77f88cbe87d581da2c6

A36C5D7B9D14E75C8D85182AA49F8893F8382B7B

Biological materials
Mutant
MGNA-B353 (ykpB::erm), available at the NBRP B. subtilis, Japan
BKE14440 (panG::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTGTGATCTCCTTTCA,  downstream forward: _UP4_TAAAAAAAGGAGGCGGAAAA
BKK14440 (panG::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTGTGATCTCCTTTCA,  downstream forward: _UP4_TAAAAAAAGGAGGCGGAAAA
GP3347 (panG::lox72 trpC2), available in Jörg Stülke's lab PubMed
GP3383 (ΔpanG::neo trpC2), available in Jörg Stülke's lab PubMed
References
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Time of last update: 2025-04-06 02:53:17

Author of last update: Jstuelk