yhxA

yhxA
168

similar to adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Locus
BSU_09260
Molecular weight
49.71 kDa
Isoelectric point
5.64
Protein length
450 aaSequenceBlast
Gene length
1350 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
yhxA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG0161 (Galperin et al., 2021)

This gene is a member of the following regulons

SigA regulon

Gene
Coordinates
1,000,364 → 1,001,716
The protein
Protein family
Class-III pyridoxal-phosphate-dependent aminotransferase family (according to UniProt)
Cofactors
PLP (according to UniProt)
Structure
3N5M (PDB) (from Bacillus Anthracis, 64% identity)
P33189 (AlphaFold)
Paralogous protein(s)
ArgD, RocD
YodT, (34,9%)
BioA, (33,6%)
GabT, (32.8%)
Additional information
subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and Regulation
Operons
Genes
yhxA-glpP
Description
PubMed
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
half-life of the mRNA: 3.7 min PubMed
half-life of the mRNA: 3.7 min PubMed
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yhxA→glpP

2025-03-01 23:11:07

ghost

64

85fa23eb85aa1c06a9e72b2b9b163d1ad44292f2

47E1A440F693CB9BD8DD6A418F32F7921D2D6BFD

Biological materials
Mutant
MGNA-B475 (yhxA::erm), available at the NBRP B. subtilis, Japan
BKE09260 (ΔyhxA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTCATTAGCGTTCCCTA,  downstream forward: _UP4_TAATATAAAAGTGAATTATT
BKK09260 (ΔyhxA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTCATTAGCGTTCCCTA,  downstream forward: _UP4_TAATATAAAAGTGAATTATT
References
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E5F6DF14A4C01B2C90F70E37908D3697BC1B5FEF

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Time of last update: 2025-04-06 02:53:22

Author of last update: Jstuelk