rapA

rapA
168

response regulator aspartate phosphatase, dephosphorylates Spo0F-P, control of the phosphorelay

Locus
BSU_12430
Molecular weight
44.81 kDa
Isoelectric point
4.85
Protein length
378 aaSequenceBlast
Gene length
1137 bpSequenceBlast
Function
control of sporulation initiation
Product
response regulator aspartate phosphatase
Essential
no
Synonyms
rapA, gsiAA, spo0L
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
1,315,869  1,317,005
The protein
Protein family
RAP family (according to UniProt)
Domains
modular organization comprising an amino terminal alpha-helical domain connected to a domain formed by six tetratrichopeptide repeats PubMed
Structure
4I9E (PDB) (RapF, 42% identity) PubMed
Q00828 (AlphaFold)
Expression and Regulation
Operons
Genes
rapA-phrA
Description
PubMed
Regulation
expressed at high cell density (ComA) PubMed
Regulatory mechanism
Spo0A: repression, PubMed, in spo0A regulon
ComA: activation, (ComA) PubMed, in comA regulon
CodY: repression, PubMed, in codY regulon
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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rapA→phrA

2025-03-17 13:18:28

ghost

94

01c2a2d5cbf2bbf9b664fb434ae4609766ddb2ba

B05E6BFE73C0264C2C2D52698EA0051DCC1003E8

Biological materials
Mutant
BKE12430 (rapA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATTAATCCCCCCTTTTGA,  downstream forward: _UP4_CAAATCCAGAGAGGAGATTG
BKK12430 (rapA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATTAATCCCCCCTTTTGA,  downstream forward: _UP4_CAAATCCAGAGAGGAGATTG
References
Reviews
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Original Publications
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25D89EF3C4D57B3E6F9AB0210029651F74356906

Page visits: 8042

Time of last update: 2025-04-10 11:42:07

Author of last update: Jstuelk