kduI

kduI
168

5-keto-4-deoxyuronate isomerase

Locus
BSU_22130
Molecular weight
30.98 kDa
Isoelectric point
5.11
Protein length
275 aaSequenceBlast
Gene length
828 bpSequenceBlast
Function
utilization of galacturonic acid
Product
5-keto-4-deoxyuronate isomerase
Essential
no
E.C.
5.3.1.17
Synonyms
kduI
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3717 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,325,854 → 2,326,681
The protein
Catalyzed reaction/ biological activity
5-dehydro-4-deoxy-D-glucuronate --> 3-deoxy-D-glycero-2,5-hexodiulosonate (according to UniProt)
Protein family
KduI family (single member, according to UniProt)
Structure
1YWK (PDB) (from Enterococcus faecalis, 48% identity)
P50843 (AlphaFold)
Expression and Regulation
Operons
Genes
kduI-kduD
Description
PubMed
Regulation
induced by galacturonate (KdgR) PubMed
Regulatory mechanism
KdgR: repression, PubMed, in kdgR regulon
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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kduI→kduD

2025-03-10 03:55:52

ghost

84

4a8739bc6783690fc74587a3d4541c259279a581

B77865E5AAA4E592F977DA1B986CD2525D071736

Biological materials
Mutant
BKE22130 (ΔkduI::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTATATTTCCCCCTTGGT,  downstream forward: _UP4_ATTCCAATGGATGGGCTGAA
BKK22130 (ΔkduI::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTATATTTCCCCCTTGGT,  downstream forward: _UP4_ATTCCAATGGATGGGCTGAA
References
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CFAEF60AD73F18C8DB5EF042210602B149D51152

Page visits: 2109

Time of last update: 2025-04-12 08:39:26

Author of last update: Melvin.boenninger