Difference between revisions of "BshA"

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* '''Additional information:'''
 
* '''Additional information:'''
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** number of protein molecules per cell (complex medium with amino acids, without glucose): 168 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 11:26, 17 April 2014

  • Description: L-malic acid glycosyltransferase, involved in bacillithiol synthesis

Gene name bshA
Synonyms jojH, ypjH
Essential no
Product L-malic acid glycosyltransferase
Function biosynthesis of bacillithiol
Gene expression levels in SubtiExpress: bshA
MW, pI 41 kDa, 6.149
Gene length, protein length 1131 bp, 377 aa
Immediate neighbours cca, bshB1
Sequences Protein DNA DNA_with_flanks
Genetic context
YpjH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BshA expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

Spx regulon


The gene

Basic information

  • Locus tag: BSU22460

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UDP-GlcNAc + L-malate = GlcNAc(α1→2)L-malate PubMed; also uses D-malate as a substrate, but with much lower affinity PubMed
  • Protein family: NamA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • subject to feedback inhibition by bacillithiol PubMed

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by diamide stess (thiol depletion) (Spx) PubMed
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 168 PubMed

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References