yhbH

yhbH
168

SigE-dependent sporulation gene

Locus
BSU_08980
Molecular weight
45.17 kDa
Isoelectric point
6.1
Protein length
392 aaSequenceBlast
Gene length
1179 bpSequenceBlast
Function
Sporulation
Product
unknown
Essential
no
Synonyms
yhbH, yzdC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2718 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
975,231  976,409
Phenotypes of a mutant
defect in sporulation PubMed
The protein
Protein family
UPF0229 family (single member, according to UniProt)
Structure
P45742 (AlphaFold)
Expression and Regulation
Operons
Genes
yhbH
Description
PubMed
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
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yhbH

2025-04-03 20:41:50

ghost

77

da66911176971e8cf000133380148ea0fdb14235

89357B7F8C17ABC72DAEBCA312510040791B322B

Biological materials
Mutant
MGNA-A734 (yhbH::erm), available at the NBRP B. subtilis, Japan
BKE08980 (yhbH::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGAATTCCCCTCCTTAAC,  downstream forward: _UP4_TAATGAAAAGCCCATTTCAG
BKK08980 (yhbH::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGAATTCCCCTCCTTAAC,  downstream forward: _UP4_TAATGAAAAGCCCATTTCAG
References
Galperin MY, Yutin N, Wolf YI, Vera Alvarez R, Koonin EVConservation and Evolution of the Sporulation Gene Set in Diverse Members of the Firmicutes.Journal of bacteriology. 2022 May 31; :e0007922. PMID: 35638784
Feucht A, Evans L, Errington J Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis. Microbiology (Reading, England). 2003 Oct; 149(Pt 10):3023-34. . PMID:14523133
Eichenberger P, Jensen ST, Conlon EM, van Ooij C, Silvaggi J, González-Pastor JE, Fujita M, Ben-Yehuda S, Stragier P, Liu JS, Losick R The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis. Journal of molecular biology. 2003 Apr 11; 327(5):945-72. . PMID:12662922
Noback MA, Holsappel S, Kiewiet R, Terpstra P, Wambutt R, Wedler H, Venema G, Bron S The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene. Microbiology (Reading, England). 1998 Apr; 144 ( Pt 4):859-75. . PMID:9579061

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Time of last update: 2025-04-04 03:57:04

Author of last update: Jstuelk