yvaK

yvaK
168

general stress protein, carboxylesterase

Locus
BSU_33620
Molecular weight
28.26 kDa
Isoelectric point
4.99
Protein length
248 aaSequenceBlast
Gene length
747 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
E.C.
3.1.1.1
Synonyms
yvaK, est, fphH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1647 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,454,221 → 3,454,967
The protein
Catalyzed reaction/ biological activity
carboxylic ester + H2O --> carboxylate + alcohol + H+ (according to UniProt)
Protein family
lipase/esterase LIP3/BchO family (single member, according to UniProt)
Structure
1TQH (PDB) (Geobacillus stearothermophilus)
8FTP (PDB) (Staphylococcus aureus) PubMed
O32232 (AlphaFold)
Expression and Regulation
Operons
Genes
secG-yvaK-rnr-smpB-ssrA
Description
PubMed
Regulation
''yvaK'': induced by stress (SigB) PubMed
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
Open in new tab

secG→ssrA

2025-04-03 20:07:29

ghost

100

5b644e318b4e03f8229d1f7804ae24c07fdeb5dd

238E5C487975E311E1EBD32D07A14F173B276AD8

Genes
yvaK-rnr-smpB-ssrA
Description
PubMed
Regulation
''yvaK'': induced by stress (SigB) PubMed
Open in new tab

yvaK→ssrA

2025-03-29 11:55:37

ghost

97

d8154c99b5174d2c9614c36d072e1652057bf9f1

E221678AD029D36CCA9613ABC361FB40A01462F7

Biological materials
Mutant
MGNA-B606 (yvaK::erm), available at the NBRP B. subtilis, Japan
BKE33620 (ΔyvaK::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGCTCATGTCTCCCTTTC,  downstream forward: _UP4_TGGTAATCAACAGGAGGTCG
BKK33620 (ΔyvaK::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGCTCATGTCTCCCTTTC,  downstream forward: _UP4_TGGTAATCAACAGGAGGTCG
References
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C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8

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Time of last update: 2025-04-10 01:28:24

Author of last update: Jstuelk