Difference between revisions of "YugJ"

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* '''Additional information:'''
 
* '''Additional information:'''
 +
** number of protein molecules per cell (minimal medium with glucose and ammonium): 1310 {{PubMed|24696501}}
 +
** number of protein molecules per cell (complex medium with amino acids, without glucose): 1788 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 09:29, 17 April 2014

  • Description: similar to NADH-dependent butanol dehydrogenase

Gene name yugJ
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yugJ
MW, pI 42 kDa, 5.221
Gene length, protein length 1161 bp, 387 aa
Immediate neighbours yugK, yuzA
Sequences Protein DNA DNA_with_flanks
Genetic context
YugJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YugJ expression.png
























Categories containing this gene/protein

poorly characterized/ putative enzymes

This gene is a member of the following regulons

Spx regulon

The gene

Basic information

  • Locus tag: BSU31370

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: iron-containing alcohol dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s): YugK

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 1310 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 1788 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Laura R Jarboe
YqhD: a broad-substrate range aldehyde reductase with various applications in production of biorenewable fuels and chemicals.
Appl Microbiol Biotechnol: 2011, 89(2);249-57
[PubMed:20924577] [WorldCat.org] [DOI] (I p)

Original publications

The corresponding protein in E. coli

Changhan Lee, Insook Kim, Junghoon Lee, Kang-Lok Lee, Bumchan Min, Chankyu Park
Transcriptional activation of the aldehyde reductase YqhD by YqhC and its implication in glyoxal metabolism of Escherichia coli K-12.
J Bacteriol: 2010, 192(16);4205-14
[PubMed:20543070] [WorldCat.org] [DOI] (I p)

José Manuel Pérez, Felipe A Arenas, Gonzalo A Pradenas, Juan M Sandoval, Claudio C Vásquez
Escherichia coli YqhD exhibits aldehyde reductase activity and protects from the harmful effect of lipid peroxidation-derived aldehydes.
J Biol Chem: 2008, 283(12);7346-53
[PubMed:18211903] [WorldCat.org] [DOI] (P p)