Nin

• Description: inhibitor of the DNA degrading activity of NucA
  
  

Gene name	nin
Synonyms	comJ
Essential	no
Product	inhibitor of the DNA degrading activity of NucA
Function	genetic transformation, DNA uptake
Gene expression levels in SubtiExpress: nin
Metabolic function and regulation of this protein in SubtiPathways: Nin
MW, pI	14 kDa, 4.922
Gene length, protein length	396 bp, 132 aa
Immediate neighbours	yckE, nucA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

genetic competence, membrane proteins, phosphoproteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

• Locus tag: BSU03420

Database entries

• BsubCyc: BSU03420

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • phosphorylated on Arg-96 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU03420

• Structure:

• UniProt: P12669

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: nucA-nin PubMed

• Expression browser: nin PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism: ComK: transcription activation PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 607 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 227 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: