Difference between revisions of "AlsS"
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− | <pubmed>19087206,10986270, 20081037,16428414, 19383131, 7685336, 16428414 19684168 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 09:29, 16 April 2014
- Description: acetolactate synthase
Gene name | alsS |
Synonyms | |
Essential | no |
Product | acetolactate synthase |
Function | overflow metabolism |
Gene expression levels in SubtiExpress: alsS | |
Metabolic function and regulation of this protein in SubtiPathways: alsS | |
MW, pI | 61 kDa, 5.164 |
Gene length, protein length | 1713 bp, 571 aa |
Immediate neighbours | alsD, alsR |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
AlsR regulon, Rex regulon, stringent response
The gene
Basic information
- Locus tag: BSU36010
Phenotypes of a mutant
Database entries
- BsubCyc: BSU36010
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2 pyruvate = 2-acetolactate + CO2 (according to Swiss-Prot)
- Protein family: TPP enzyme family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU36010
- Structure:
- UniProt: Q04789
- KEGG entry: [3]
- E.C. number: 2.2.1.6
Additional information
Expression and regulation
- Regulation:
Note: since acetate formation requires ackA activation by CcpA there is an indirect effect of CcpA on the alsSD operon: the operon is not expressed in ccpA mutants
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References