fhuB

fhuB
168

hydroxamate siderophore ABC transporter (ferrichrome und ferrioxamine) (permease)

Locus
BSU_33310
Molecular weight
40.56 kDa
Isoelectric point
10.14
Protein length
384 aaSequenceBlast
Gene length
1155 bpSequenceBlast
Function
siderophore uptake
Product
hydroxamate siderophore ABC transporter  (ferrichrome und ferrioxamine) (permease)
Essential
no
Synonyms
fhuB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0609 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,417,222  3,418,376
The protein
Protein family
Binding-protein-dependent transport system permease family (according to UniProt)
FecCD subfamily (according to UniProt)
Structure
4G1U (PDB) (from Yersinia pestis, 37% identity) PubMed
P49936 (AlphaFold)
Paralogous protein(s)
FeuB, YfiZ, FecD
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
fhuB-fhuG-fhuC
Description
PubMed
Regulation
induced by iron starvation (second wave to allow iron scavenging from the environment) (Fur) PubMed
Regulatory mechanism
Fur: repression, PubMed, in fur regulon
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fhuB-fhuG-fhuC

2025-03-26 04:16:32

Jstuelk

68

e98119b29266bf1ea636fb20c7dd12b77bf9d9ea

6298E2AA0515AFDCFE83761F5E184811F4A90D9E

Biological materials
Mutant
BKE33310 (fhuB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGCAAAAATATCGTGT,  downstream forward: _UP4_CGTCGTGAAAGGAGAGGGCT
BKK33310 (fhuB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGCAAAAATATCGTGT,  downstream forward: _UP4_CGTCGTGAAAGGAGAGGGCT
References
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3E1C925C31C00803982C8EB1C6B025C22DB4A828

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Time of last update: 2025-04-06 03:29:21

Author of last update: Jstuelk