Difference between revisions of "EfeU"
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| − | * '''Description:''' elemental iron uptake system (permease) <br/><br/> | + | * '''Description:''' elemental iron uptake system (permease), high affinity uptake of ferric iron (Fe(III)) <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || elemental iron uptake system (permease) | |style="background:#ABCDEF;" align="center"| '''Product''' || elemental iron uptake system (permease) | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || iron uptake | + | |style="background:#ABCDEF;" align="center"|'''Function''' || elemental iron uptake |
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38280 efeU] |
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/EfeU EfeU] |
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=EfeU EfeU]''' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 8.958 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 8.958 | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1443 bp, 481 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1443 bp, 481 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[efeO]]'', ''[[thiE]]'' |
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38280 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38280 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38280 DNA_with_flanks] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ywbL_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ywbL_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
|- | |- | ||
| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=efeU_3929105_3930550_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:ywbL_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=efeU_3929105_3930550_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:ywbL_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38280]] |
|- | |- | ||
|} | |} | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| − | ** | + | ** [[EfeO]]-[[EfeU]]-[[EfeB]] {{PubMed|23180473,23764491}} |
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| Line 111: | Line 111: | ||
=Expression and regulation= | =Expression and regulation= | ||
* '''Operon:''' | * '''Operon:''' | ||
| − | ** ''[[ | + | ** ''[[efeU]]-[[efeO]]-[[efeB]]'' {{PubMed|9353933}} |
| − | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=efeU_3929105_3930550_-1 | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=efeU_3929105_3930550_-1 efeU] {{PubMed|22383849}} |
| − | * '''Sigma factor:''' | + | * '''Sigma factor:''' [[SigA]] {{PubMed|23764491}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 145: | Line 145: | ||
=References= | =References= | ||
| − | <pubmed>16672620,23180473,12354229, </pubmed> | + | <pubmed>16672620,23180473,12354229, 23764491</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Latest revision as of 11:45, 8 April 2014
- Description: elemental iron uptake system (permease), high affinity uptake of ferric iron (Fe(III))
| Gene name | ywbL |
| Synonyms | ipa-27d |
| Essential | no |
| Product | elemental iron uptake system (permease) |
| Function | elemental iron uptake |
| Gene expression levels in SubtiExpress: efeU | |
| Interactions involving this protein in SubtInteract: EfeU | |
| Metabolic function and regulation of this protein in SubtiPathways: EfeU | |
| MW, pI | 52 kDa, 8.958 |
| Gene length, protein length | 1443 bp, 481 aa |
| Immediate neighbours | efeO, thiE |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transporters/ other, acquisition of iron, iron metabolism, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38280
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39595
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Marcus Miethke, Carmine G Monteferrante, Mohamed A Marahiel, Jan Maarten van Dijl
The Bacillus subtilis EfeUOB transporter is essential for high-affinity acquisition of ferrous and ferric iron.
Biochim Biophys Acta: 2013, 1833(10);2267-78
[PubMed:23764491]
[WorldCat.org]
[DOI]
(P p)
Carmine G Monteferrante, Calum MacKichan, Elodie Marchadier, Maria-Victoria Prejean, Rut Carballido-López, Jan Maarten van Dijl
Mapping the twin-arginine protein translocation network of Bacillus subtilis.
Proteomics: 2013, 13(5);800-11
[PubMed:23180473]
[WorldCat.org]
[DOI]
(I p)
Juliane Ollinger, Kyung-Bok Song, Haike Antelmann, Michael Hecker, John D Helmann
Role of the Fur regulon in iron transport in Bacillus subtilis.
J Bacteriol: 2006, 188(10);3664-73
[PubMed:16672620]
[WorldCat.org]
[DOI]
(P p)
Noel Baichoo, Tao Wang, Rick Ye, John D Helmann
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Mol Microbiol: 2002, 45(6);1613-29
[PubMed:12354229]
[WorldCat.org]
[DOI]
(P p)
