AraR

• Description: repressor of the arabinose utilization genes
  
  

Gene name	araR
Synonyms	araC, yvbS
Essential	no
Product	transcriptional repressor (GntR family, LacI family)
Function	regulation of arabinose utilization (araABDLMNPQ-abfA) and of the araE/araR genes
Gene expression levels in SubtiExpress: araR (araABDLMNPQ-abfA) and of the araE/araR genes
Metabolic function and regulation of this protein in SubtiPathways: AraR
MW, pI	43 kDa, 6.341
Gene length, protein length	1152 bp, 384 aa
Immediate neighbours	araE, yvbT
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

AraR regulon

The gene

Basic information

• Locus tag: BSU33970

Database entries

• BsubCyc: BSU33970

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GntR family: N-terminal DNA-binding domain, LacI family: C-terminal effector-binding domain

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • N-terminal DNA-binding domain (GntR family)
  • C-terminal effector-binding domain (LacI family)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU33970

• Structure: 3TB6 (effector-binding domain) PubMed

• UniProt: P96711

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: araR PubMed

• Expression browser: araR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by arabinose (AraR) PubMed

• Regulatory mechanism:
  • AraR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed