ganQ

ganQ
168

galactotriose ABC transporter (permease)

Locus
BSU_34140
Molecular weight
31.15 kDa
Isoelectric point
9.76
Protein length
283 aaSequenceBlast
Gene length
852 bpSequenceBlast
Function
uptake of galactotriose
Product
galactotriose ABC transporter (permease)
Essential
no
Synonyms
ganQ, yvfM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3833 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,505,102  3,505,953
Phenotypes of a mutant
a ''ganS-ganP-ganQ-ganA-ganB'' mutant is impaired in the utilization of galactan PubMed
The protein
Protein family
Binding-protein-dependent transport system permease family (according to UniProt)
Domains
ABC transmembrane type-1 domain (aa 76-268) (according to UniProt)
Structure
2R6G (PDB) (from E. coli, 34% identity) PubMed
O07011 (AlphaFold)
Paralogous protein(s)
MdxG
Localization
cell membrane PubMed
Expression and Regulation
Operons
Genes
ganS-ganP-ganQ-ganA-ganB
Description
PubMed
Regulation
induced by galactan (binding of galactobiose to GanR) PubMed
repressed by glucose (CcpA) PubMed
Regulatory mechanism
GanR: repression, PubMed, in ganR regulon
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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ganS→ganB

2025-04-09 00:22:07

Jstuelk

99

8098d66636fb8292b3a8cdd7bc3488e2a6cd4b3a

CC7DD5B518C2C1EF65E89AEC569B449F25EC1495

Biological materials
Mutant
MGNA-A486 (yvfM::erm), available at the NBRP B. subtilis, Japan
BKE34140 (ganQ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GACTTTCATATCTGCCAGCA,  downstream forward: _UP4_GGCTAAGAGAACAAGGAGGA
BKK34140 (ganQ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GACTTTCATATCTGCCAGCA,  downstream forward: _UP4_GGCTAAGAGAACAAGGAGGA
References
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Time of last update: 2025-04-13 06:22:58

Author of last update: Jstuelk