yvfU

yvfU
168

two-component response regulator

Locus
BSU_34060
Molecular weight
22.18 kDa
Isoelectric point
5.08
Protein length
200 aaSequenceBlast
Gene length
603 bpSequenceBlast
Function
unknown
Product
two-component response regulator
Essential
no
Synonyms
yvfU
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2197 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,495,876  3,496,478
The protein
Domains
Response regulatory domain (aa 3-119) (according to UniProt)
HTH luxR-type domain (aa 133-198) (according to UniProt)
Structure
4LDZ (PDB) (DesR, 59% identity) PubMed
O07019 (AlphaFold)
Modification
phosphorylated on Arg-116 and Arg-143 (phosphorylation serves as tag for degradation by ClpC-ClpP) PubMed
phosphorylated by YvfT on an Asp residue PubMed
Paralogous protein(s)
DesR
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
yvfT-yvfU
Description
PubMed
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yvfT→yvfU

2025-04-01 19:18:21

Jstuelk

11

E271FBCE673912F89723BA42A72E80258A9AEEBC

E271FBCE673912F89723BA42A72E80258A9AEEBC

Biological materials
Mutant
MGNA-A496 (yvfU::erm), available at the NBRP B. subtilis, Japan
BKE34060 (yvfU::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACGAATCATTCTTTTCGTCC,  downstream forward: _UP4_TAACCATATACTGCACTCCT
BKK34060 (yvfU::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACGAATCATTCTTTTCGTCC,  downstream forward: _UP4_TAACCATATACTGCACTCCT
References
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Page visits: 2068

Time of last update: 2025-04-10 16:43:07

Author of last update: Jstuelk