Difference between revisions of "ComX"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU31700&redirect=T BSU31700]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/comQX.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/comQX.html]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU31700&redirect=T BSU31700]
  
 
* '''Structure:'''
 
* '''Structure:'''

Revision as of 14:38, 2 April 2014

  • Description: competence pheromone precursor, transfers cell density signal to ComP; triggers the production of surfactin

Gene name comX
Synonyms
Essential no
Product competence pheromone precursor
Function quorum sensing
Gene expression levels in SubtiExpress: comX
Interactions involving this protein in SubtInteract: ComX
MW, pI 6 kDa, 4.358
Gene length, protein length 165 bp, 55 aa
Immediate neighbours comP, comQ
Sequences Protein DNA DNA_with_flanks
Genetic context
ComX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComX expression.png















Categories containing this gene/protein

genetic competence, quorum sensing

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU31700

Phenotypes of a mutant

  • the mutation suppresses the mucoid phenotype of motA or motB mutants due to loss of DegU phosphorylation and concomitant reduced expression of the capB-capC-capA-capE operon PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
    • is synthesized as an inactive precursor, cleaved, and modified (prenylated) by ComQ prior to excretion PubMed
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

The ComX --> surfactin signaling pathway is an example for paracrine signaling in bacteria

References

Reviews

Original publications