MrpA

• Description: Na+ transporter subunit of the Na+/H+ antiporter, multiple resistance and pH homeostasis
  
  

Gene name	mrpA
Synonyms	yufT, shaA, ntrA
Essential	yes PubMed
Product	Na+/H+ antiporter subunit
Function	sodium export
Gene expression levels in SubtiExpress: mrpA
Interactions involving this protein in SubtInteract: MrpA
MW, pI	86 kDa, 9.519
Gene length, protein length	2322 bp, 774 aa
Immediate neighbours	yufS, mrpB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU31600

Phenotypes of a mutant

• essential PubMed
• a mrpA mutant is viable at pH7.4 and sodium concentrations below 80 mM PubMed
• the mrpA mutant accumulates internal sodium PubMed

Database entries

• BsubCyc: BSU31600

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Na+ transporter subunit of the Na+/H+ antiporter PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • MrpA-MrpB-MrpC-MrpD-MrpE-MrpF-MrpG (complex)

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU31600

• Structure:

• UniProt: Q9K2S2

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: mrpA-mrpB-mrpC-mrpD-mrpE-mrpF-mrpG PubMed

• Expression browser: mrpA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: