glgC

glgC
168

glucose-1-phosphate adenylyltransferase

Locus
BSU_30970
Molecular weight
42.44 kDa
Isoelectric point
4.86
Protein length
380 aaSequenceBlast
Gene length
1143 bpSequenceBlast
Function
glycogen biosynthesis
Product
glucose-1-phosphate adenylyltransferase
Essential
no
E.C.
2.7.7.27
Synonyms
glgC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0448 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,168,624 → 3,169,766
The protein
Catalyzed reaction/ biological activity
α-D-glucose 1-phosphate + ATP + H+ --> ADP-α-D-glucose + diphosphate (according to UniProt)
Protein family
bacterial/plant glucose-1-phosphate adenylyltransferase family (with GlgD, according to UniProt)
Structure
5L6S (PDB) (E. coli ADP-glucose pyrophosphorylase, 41% identity) PubMed
P39122 (AlphaFold)
Paralogous protein(s)
GlgD
Expression and Regulation
Operons
Genes
glgB-glgC-glgD-glgA-glgP
Description
PubMed
Regulation
expressed early during sporulation in the mother cell (SigE) PubMed
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
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glgB→glgP

2025-04-04 08:53:26

ghost

78

fffeb17cb5b6051e783d59196d95d7090a27b1c0

1789CF3539E2172289FC51E8FA1F9C213683180D

Biological materials
Mutant
BKE30970 (ΔglgC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GAGCATGGCTACACATTGTT,  downstream forward: _UP4_TAATTACTGAAGAGGGGGCA
BKK30970 (ΔglgC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GAGCATGGCTACACATTGTT,  downstream forward: _UP4_TAATTACTGAAGAGGGGGCA
References
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Time of last update: 2025-04-16 15:51:41

Author of last update: Melvin.boenninger