Difference between revisions of "MenF"

From SubtiWiki
Jump to: navigation, search
Line 58: Line 58:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30830&redirect=T BSU30830]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/menBEC.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/menBEC.html]
Line 95: Line 96:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30830&redirect=T BSU30830]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3BZM 3BZM] (from ''Escherichia coli'', 33% identity, 51% similarity) {{PubMed|18453696}}
 
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3BZM 3BZM] (from ''Escherichia coli'', 33% identity, 51% similarity) {{PubMed|18453696}}

Revision as of 14:35, 2 April 2014

  • Description: menaquinone-specific isochorismate synthase

Gene name menF
Synonyms icsM, entC
Essential no
Product menaquinone-specific isochorismate synthase
Function biosynthesis of menaquinone
Gene expression levels in SubtiExpress: menF
Metabolic function and regulation of this protein in SubtiPathways:
menF
MW, pI 52 kDa, 4.706
Gene length, protein length 1413 bp, 471 aa
Immediate neighbours menD, yteA
Sequences Protein DNA DNA_with_flanks
Genetic context
MenF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MenF expression.png




























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU30830

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Chorismate = isochorismate (according to Swiss-Prot)
  • Protein family: isochorismate synthase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3BZM (from Escherichia coli, 33% identity, 51% similarity) PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221] [WorldCat.org] [DOI] (P p)

X Qin, H W Taber
Transcriptional regulation of the Bacillus subtilis menp1 promoter.
J Bacteriol: 1996, 178(3);705-13
[PubMed:8550504] [WorldCat.org] [DOI] (P p)

J R Driscoll, H W Taber
Sequence organization and regulation of the Bacillus subtilis menBE operon.
J Bacteriol: 1992, 174(15);5063-71
[PubMed:1629163] [WorldCat.org] [DOI] (P p)