Difference between revisions of "LuxS"

From SubtiWiki
Jump to: navigation, search
Line 61: Line 61:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30670&redirect=T BSU30670]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/luxS.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/luxS.html]
Line 95: Line 96:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30670&redirect=T BSU30670]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1JQW 1JQW] (complex with homocysteine),  [http://www.rcsb.org/pdb/explore.do?structureId=1J98 1J98]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1JQW 1JQW] (complex with homocysteine),  [http://www.rcsb.org/pdb/explore.do?structureId=1J98 1J98]

Revision as of 14:35, 2 April 2014

  • Description: S-ribosylhomocysteine lyase, autoinducer-2 production protein, required for swarming motility and biofilm formation

Gene name luxS
Synonyms ytjB
Essential no
Product S-ribosylhomocysteine lyase
Function methionine salvage
Gene expression levels in SubtiExpress: luxS
Metabolic function and regulation of this protein in SubtiPathways:
luxS
MW, pI 17 kDa, 5.168
Gene length, protein length 471 bp, 157 aa
Immediate neighbours ytkA, ytjA
Sequences Protein DNA DNA_with_flanks
Genetic context
LuxS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
500px




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, motility and chemotaxis, quorum sensing, biofilm formation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU30670

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione (according to Swiss-Prot)
  • Protein family: luxS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: subject to feedback inhibition PubMed

Database entries

  • Structure: 1JQW (complex with homocysteine), 1J98
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: subject to feedback inhibition PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References