Difference between revisions of "ThrS"
| Line 57: | Line 57: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28950&redirect=T BSU28950] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/thrS.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/thrS.html] | ||
| Line 91: | Line 92: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28950&redirect=T BSU28950] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TJE 1TJE] (from ''Escherichia coli'', 44% identity, 63% similarity) {{PubMed|15525511}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TJE 1TJE] (from ''Escherichia coli'', 44% identity, 63% similarity) {{PubMed|15525511}} | ||
Revision as of 14:28, 2 April 2014
- Description: threonyl-tRNA synthetase (major)
| Gene name | thrS |
| Synonyms | |
| Essential | no |
| Product | threonyl-tRNA synthetase (major) |
| Function | translation |
| Gene expression levels in SubtiExpress: thrS | |
| Metabolic function and regulation of this protein in SubtiPathways: thrS | |
| MW, pI | 73 kDa, 5.214 |
| Gene length, protein length | 1929 bp, 643 aa |
| Immediate neighbours | ysaA, ytxC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
translation, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28950
Phenotypes of a mutant
Database entries
- BsubCyc: BSU28950
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr) (according to Swiss-Prot)
- Protein family: class-II aminoacyl-tRNA synthetase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Modification:Cys573 is S-bacillithiolated by NaOCl stress PubMed
- Effectors of protein activity:
Database entries
- BsubCyc: BSU28950
- UniProt: P18255
- KEGG entry: [3]
- E.C. number: 6.1.1.3
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Regulation:
- Regulatory mechanism:
- T-box: RNA switch, transcriptional antitermination PubMed
- Additional information:
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
