Difference between revisions of "GreA"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27320&redirect=T BSU27320] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27320&redirect=T BSU27320] | ||
* '''Structure:''' | * '''Structure:''' | ||
Revision as of 14:21, 2 April 2014
- Description: transcription elongation factor, resolves stalled RNA polymerase at promoter or promoter-proximal regions,
| Gene name | greA |
| Synonyms | |
| Essential | no |
| Product | transcription elongation factor |
| Function | transcription elongation |
| Gene expression levels in SubtiExpress: greA | |
| MW, pI | 17 kDa, 4.475 |
| Gene length, protein length | 471 bp, 157 aa |
| Immediate neighbours | pbpI, udk |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27320
Phenotypes of a mutant
- RNA polymerase accumulates in promoter-proximal regions of many genes PubMed
Database entries
- BsubCyc: BSU27320
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: greA/greB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: uniformly distributed throughout the nucleoid PubMed
Database entries
- BsubCyc: BSU27320
- Structure:
- UniProt: P80240
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Padraig Deighan, Ann Hochschild
Conformational toggle triggers a modulator of RNA polymerase activity.
Trends Biochem Sci: 2006, 31(8);424-6
[PubMed:16815708]
[WorldCat.org]
[DOI]
(P p)
Sergei Borukhov, Jookyung Lee, Oleg Laptenko
Bacterial transcription elongation factors: new insights into molecular mechanism of action.
Mol Microbiol: 2005, 55(5);1315-24
[PubMed:15720542]
[WorldCat.org]
[DOI]
(P p)
Bryce E Nickels, Ann Hochschild
Regulation of RNA polymerase through the secondary channel.
Cell: 2004, 118(3);281-4
[PubMed:15294154]
[WorldCat.org]
[DOI]
(P p)
Original Publications
