YqcF

• Description: antitoxin
  
  

Gene name	yqcF
Synonyms
Essential	no
Product	antitoxin
Function	inhibition of the cytotoxic activity of YqcG
Gene expression levels in SubtiExpress: yqcF
Interactions involving this protein in SubtInteract: YqcF
MW, pI	21 kDa, 4.268
Gene length, protein length	576 bp, 192 aa
Immediate neighbours	yqcG, yqxJ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, Skin element

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

• Locus tag: BSU25870

Database entries

• BsubCyc: BSU25870

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YqcG-YqcF PubMed

• Localization:

Database entries

• BsubCyc: BSU25870

• Structure:

• UniProt: P45941

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yqcG-yqcF (according to DBTBS)

• Expression browser: yqcF PubMed

• Sigma factor:

• Regulation:
  • expressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism:
  • Spo0A: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Laura E Holberger, Fernando Garza-Sánchez, James Lamoureux, David A Low, Christopher S Hayes
A novel family of toxin/antitoxin proteins in Bacillus species.
FEBS Lett: 2012, 586(2);132-6
[PubMed:22200572] [WorldCat.org] [DOI] (I p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)