Difference between revisions of "ArsC"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25780&redirect=T BSU25780]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/arsR-yqcK-arsBC.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/arsR-yqcK-arsBC.html]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25780&redirect=T BSU25780]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1Z2D 1Z2D] (reduced form),  [http://www.rcsb.org/pdb/explore.do?structureId=1Z2E 1Z2E] (oxidized form),  [http://www.rcsb.org/pdb/explore.do?structureId=2IPA 2IPA] (TrxA-ArsC-complex) {{PubMed|17303556}},  [http://www.rcsb.org/pdb/explore.do?structureId=1JL3 1JL3]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1Z2D 1Z2D] (reduced form),  [http://www.rcsb.org/pdb/explore.do?structureId=1Z2E 1Z2E] (oxidized form),  [http://www.rcsb.org/pdb/explore.do?structureId=2IPA 2IPA] (TrxA-ArsC-complex) {{PubMed|17303556}},  [http://www.rcsb.org/pdb/explore.do?structureId=1JL3 1JL3]

Revision as of 14:17, 2 April 2014

  • Description: arsenate reductase

Gene name arsC
Synonyms yqcM
Essential no
Product arsenate reductase
Function detoxification of arsenate
Gene expression levels in SubtiExpress: arsC
Interactions involving this protein in SubtInteract: ArsC
MW, pI 15 kDa, 4.749
Gene length, protein length 417 bp, 139 aa
Immediate neighbours spoIVCA, arsB
Sequences Protein DNA DNA_with_flanks
Genetic context
ArsC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ArsC expression.png
























Categories containing this gene/protein

resistance against toxic metals, Skin element

This gene is a member of the following regulons

ArsR regulon, SigF regulon

The gene

Basic information

  • Locus tag: BSU25780

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot)
  • Protein family: ArsC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the forespore (SigF) PubMed
    • expressed in the presence of toxic metal ions (As(III), Cd(II) and Ag(I)) (ArsR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed