spoIIM

spoIIM
168

required for dissolution of the septal cell wall and for ribosome translocation to the forespore

Locus
BSU_23530
Molecular weight
24.15 kDa
Isoelectric point
9.84
Protein length
214 aaSequenceBlast
Gene length
645 bpSequenceBlast
Function
dissolution of the septal cell wall
Product
sporulation protein
Essential
no
Synonyms
spoIIM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1300 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,450,403  2,451,047
The protein
Structure
P37873 (AlphaFold)
Localization
cytoplasm (according to Swiss-Prot)
the complex of SpoIID, SpoIIM, and SpoIIP localizes at the leading edge of the mother cell engulfing membrane and is essential and rate limiting for membrane migration PubMed
localization of the SpoIID-SpoIIM-SpoIIP complex to the septal membrane depends on SpoIIB PubMed
Expression and Regulation
Operons
Genes
spoIIM
Description
PubMed
Regulation
expressed early during sporulation in the mother cell (SigE) PubMed
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
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spoIIM

2025-03-16 17:27:04

ghost

74

0df3a69b2f25a7ddde040ed934a52ebd38f0e38e

2EA25BC4093A38E6DF05E0D7A9811BD7AE9DDBBD

Biological materials
Mutant
MGNA-C416 (spoIIM::erm), available at the NBRP B. subtilis, Japan
BKE23530 (spoIIM::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACCGTTTCCTCCCGCCC,  downstream forward: _UP4_TAAAATCATTATTAAAAGAA
BKK23530 (spoIIM::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACCGTTTCCTCCCGCCC,  downstream forward: _UP4_TAAAATCATTATTAAAAGAA
References
Reviews
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Original Publications
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14852D54F8B7344AA80D535F8EBBCE11E2B859CF

Page visits: 2653

Time of last update: 2025-04-06 16:05:44

Author of last update: Jstuelk