Difference between revisions of "RibH"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU23250&redirect=T BSU23250]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ypuE-ribDEAHT.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ypuE-ribDEAHT.html]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU23250&redirect=T BSU23250]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1zis 1ZIS], [http://www.rcsb.org/pdb/explore.do?structureId=1RVV 1RVV] (the [[RibE]])3-([[RibH]])60 lumazine synthase/riboflavin synthase complex) {{PubMed|7473709}}
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1zis 1ZIS], [http://www.rcsb.org/pdb/explore.do?structureId=1RVV 1RVV] (the [[RibE]])3-([[RibH]])60 lumazine synthase/riboflavin synthase complex) {{PubMed|7473709}}

Revision as of 14:06, 2 April 2014

  • Description: riboflavin synthase (beta subunit)

Gene name ribH
Synonyms
Essential no
Product riboflavin synthase (beta subunit)
Function riboflavin biosynthesis
Gene expression levels in SubtiExpress: ribH
Interactions involving this protein in SubtInteract: RibH
Metabolic function and regulation of this protein in SubtiPathways:
ribH
MW, pI 16 kDa, 5.196
Gene length, protein length 462 bp, 154 aa
Immediate neighbours ribT, ribA
Sequences Protein DNA DNA_with_flanks
Genetic context
RibH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RibH expression.png















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

FMN-box

The gene

Basic information

  • Locus tag: BSU23250

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine (according to Swiss-Prot)
  • Protein family: DMRL synthase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism: FMN-box: riboswitch, mediates termination/ antitermination control of the operon, in the absence of FMN: antitermination, in the presence of FMN: termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References