Difference between revisions of "FolE"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22780&redirect=T BSU22780] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mtrAB.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mtrAB.html] | ||
| Line 95: | Line 96: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22780&redirect=T BSU22780] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3D2O 3D2O] (enzyme from ''Neisseria gonorrhoeae'') {{PubMed|17032654}} | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3D2O 3D2O] (enzyme from ''Neisseria gonorrhoeae'') {{PubMed|17032654}} | ||
Revision as of 14:04, 2 April 2014
- Description: GTP cyclohydrolase I
| Gene name | folE |
| Synonyms | mtrA |
| Essential | no |
| Product | GTP cyclohydrolase IA |
| Function | biosynthesis of folate |
| Gene expression levels in SubtiExpress: folE | |
| Metabolic function and regulation of this protein in SubtiPathways: folE | |
| MW, pI | 21 kDa, 6.335 |
| Gene length, protein length | 570 bp, 190 aa |
| Immediate neighbours | mtrB, hbs |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22780
Phenotypes of a mutant
Database entries
- BsubCyc: BSU22780
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate (according to Swiss-Prot)
- Protein family: citrate synthase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): zinc-dependent enzyme PubMed
- Effectors of protein activity:
Database entries
- BsubCyc: BSU22780
- UniProt: P19465
- KEGG entry: [3]
- E.C. number: 3.5.4.16
Additional information
Expression and regulation
- Regulation: constitutive PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
