Difference between revisions of "MotB"
| Line 57: | Line 57: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13680&redirect=T BSU13680] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/motAB.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/motAB.html] | ||
| Line 93: | Line 94: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13680&redirect=T BSU13680] | ||
* '''Structure:''' | * '''Structure:''' | ||
Revision as of 13:33, 2 April 2014
| Gene name | motB |
| Synonyms | mot |
| Essential | no |
| Product | motility protein (flagellar motor rotation) |
| Function | motility and chemotaxis |
| Gene expression levels in SubtiExpress: motB | |
| Interactions involving this protein in SubtInteract: MotB | |
| MW, pI | 29 kDa, 6.652 |
| Gene length, protein length | 783 bp, 261 aa |
| Immediate neighbours | mhqR, motA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
motility and chemotaxis, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13680
Phenotypes of a mutant
- loss of swimming and swarming motility PubMed
- mucoid phenotype due to the DegU-P activated overexpression of the capB-capC-capA-capE operon and resulting overproduction of poly-gamma-glutamate PubMed
Database entries
- BsubCyc: BSU13680
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: OmpA-like domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- protonation of Asp-24 is essential for torque generation PubMed
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- BsubCyc: BSU13680
- Structure:
- UniProt: P28612
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: available in Nicola Stanley-Wall's lab PubMed
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jia Mun Chan, Sarah B Guttenplan, Daniel B Kearns
Defects in the flagellar motor increase synthesis of poly-γ-glutamate in Bacillus subtilis.
J Bacteriol: 2014, 196(4);740-53
[PubMed:24296669]
[WorldCat.org]
[DOI]
(I p)
Lynne S Cairns, Victoria L Marlow, Emma Bissett, Adam Ostrowski, Nicola R Stanley-Wall
A mechanical signal transmitted by the flagellum controls signalling in Bacillus subtilis.
Mol Microbiol: 2013, 90(1);6-21
[PubMed:23888912]
[WorldCat.org]
[DOI]
(I p)
J Zhou, L L Sharp, H L Tang, S A Lloyd, S Billings, T F Braun, D F Blair
Function of protonatable residues in the flagellar motor of Escherichia coli: a critical role for Asp 32 of MotB.
J Bacteriol: 1998, 180(10);2729-35
[PubMed:9573160]
[WorldCat.org]
[DOI]
(P p)
M Z Gilman, M J Chamberlin
Developmental and genetic regulation of Bacillus subtilis genes transcribed by sigma 28-RNA polymerase.
Cell: 1983, 35(1);285-93
[PubMed:6313226]
[WorldCat.org]
[DOI]
(P p)
