cotX

cotX
168

spore crust protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat

Locus
BSU_11760
Molecular weight
18.46 kDa
Isoelectric point
4.23
Protein length
172 aaSequenceBlast
Gene length
519 bpSequenceBlast
Function
spore crust assembly
Product
spore crust protein (insoluble fraction)
Essential
no
Synonyms
cotX
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5886 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,250,656  1,251,174
The protein
Structure
Q08313 (AlphaFold)
Modification
contains a glycosylation motif PubMed
Localization
spore crust with a preference for spore poles PubMed
Expression and Regulation
Operons
Genes
cotX
Description
PubMed
Regulation
expressed late during sporulation (SigE, SigK, GerE, GerR) PubMed
Regulatory mechanism
GerE: activation, PubMed, in gerE regulon
GerR: activation, PubMed, in gerR regulon
Sigma factors
SigK: sigma factor, before CotV PubMed, in sigK regulon
SigE: sigma factor, before CotV, in sigE regulon
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cotX

2025-03-17 12:21:49

ghost

88

3ab0dc2db753765452db008eeb72f94a07034af0

552EFC63979CA8AFECC0CC5545AE6D831AB6DA46

Genes
cotV-cotW-cotX
Description
PubMed
Regulation
expressed during sporulation in the mother cell (SigE, SigK, GerE, SpoIIID) PubMed
Regulatory mechanism
GerE: activation, PubMed, in gerE regulon
SpoIIID: activation, PubMed, in spoIIID regulon
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
SigE: sigma factor, PubMed, in sigE regulon
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cotV→cotX

2025-04-04 15:34:08

ghost

68

d2c258d06ac9b622812dc5167b67f8b6cda6f5a0

A452B6601F16F2096F9BDD8987ADC1AB0BEF1DBD

Biological materials
Mutant
BKE11760 (cotX::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATCTATTCCTCCTTTTC,  downstream forward: _UP4_TAGGACCTAAAAGCAGAGCT
BKK11760 (cotX::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATCTATTCCTCCTTTTC,  downstream forward: _UP4_TAGGACCTAAAAGCAGAGCT
References
Reviews
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Original Publications
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905148CAF82018E7F8E800FDF3F41163AAA8E682

Page visits: 4107

Time of last update: 2025-04-10 04:02:37

Author of last update: Jstuelk