opuE

opuE
168

proline transporter

Locus
BSU_06660
Molecular weight
53.12 kDa
Isoelectric point
9.81
Protein length
492 aaSequenceBlast
Gene length
1479 bpSequenceBlast
Function
compatible solute transport
Product
proline transporter
Essential
no
Synonyms
opuE, yerK
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0591 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
726,840  728,318
Phenotypes of a mutant
strong growth disadvantage in high-salinity minimal media lacking proline PubMed
The protein
Protein family
sodium:solute symporter (SSF) (TC 2.A.21) family (according to UniProt)
Structure
O06493 (AlphaFold)
Paralogous protein(s)
PutP
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
opuE
Description
PubMed
Regulation
induced by glucose (CcpA) PubMed
Regulatory mechanism
CcpA: activation, PubMed, in ccpA regulon
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
Additional information
the mRNA is very stable (half-life > 15 min) PubMed
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opuE

2025-04-05 22:46:24

ghost

119

4371b776c104e79e77889ccb95558d0e15e1e5fc

89417D1ED9EEFA62675D65EC2631C80FC5E615E8

Biological materials
Mutant
GP4688 (trpC2 ΔopuE::neo), available in Jörg Stülke's lab
available in Erhard Bremer's lab PubMed
BKE06660 (opuE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACGTTTTACCCTCTCTTCA,  downstream forward: _UP4_TAAGCAATAAGCCATCAAGC
BKK06660 (opuE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACGTTTTACCCTCTCTTCA,  downstream forward: _UP4_TAAGCAATAAGCCATCAAGC
Labs working on this gene/protein
Erhard Bremer, University of Marburg, Germany homepage
References
Reviews
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Original Publications
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6A1F759DAC09D364602460E5467E2761E97CE45C

Page visits: 4939

Time of last update: 2025-04-06 00:42:10

Author of last update: Robert.warneke