ydbS

ydbS
168

resistence against antimicrobial compounds from B. amyloliquefaciens

Locus
BSU_04590
Molecular weight
17.98 kDa
Isoelectric point
8.13
Protein length
159 aaSequenceBlast
Gene length
480 bpSequenceBlast
Function
confers resistence against antimicrobial compounds from B. amyloliquefaciens
Product
unknown
Essential
no
E.C.
null
Synonyms
ydbS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3402 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
512,814 → 513,293
The protein
Protein family
UPF0699 family (with YdbT, according to UniProt)
Structure
P96615 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
ydbS-ydbT
Description
PubMed
Sigma factors
SigW: sigma factor, PubMed, in sigW regulon
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ydbS→ydbT

2025-04-03 13:32:28

ghost

99

687bcf606d3cd5a448ab026ec70f901160db5f87

F60B1757D84E3B8F40084D5EEE2410BE14586A6E

Biological materials
Mutant
MGNA-C100 (ydbS::erm), available at the NBRP B. subtilis, Japan
BKE04590 (ΔydbS::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAAATACCTACCTCCCTT,  downstream forward: _UP4_TCCCGTCTGGCGAGGGTGAC
BKK04590 (ΔydbS::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAAATACCTACCTCCCTT,  downstream forward: _UP4_TCCCGTCTGGCGAGGGTGAC
References
Butcher BG, Helmann JD Identification of Bacillus subtilis sigma-dependent genes that provide intrinsic resistance to antimicrobial compounds produced by Bacilli. Molecular microbiology. 2006 May; 60(3):765-82. . PMID:16629676
Cao M, Wang T, Ye R, Helmann JD Antibiotics that inhibit cell wall biosynthesis induce expression of the Bacillus subtilis sigma(W) and sigma(M) regulons. Molecular microbiology. 2002 Sep; 45(5):1267-76. . PMID:12207695
Cao M, Kobel PA, Morshedi MM, Wu MF, Paddon C, Helmann JD Defining the Bacillus subtilis sigma(W) regulon: a comparative analysis of promoter consensus search, run-off transcription/macroarray analysis (ROMA), and transcriptional profiling approaches. Journal of molecular biology. 2002 Feb 22; 316(3):443-57. . PMID:11866510

E4139214AB491712309F84A0792BCD8939F634D7

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Time of last update: 2025-04-10 16:17:47

Author of last update: Melvin.boenninger