phrC

phrC
168

response regulator aspartate phosphatase (RapC) regulator / competence and sporulation stimulating factor (CSF)

Locus
BSU_03780
Molecular weight
4.06 kDa
Isoelectric point
8.16
Protein length
40 aaSequenceBlast
Gene length
123 bpSequenceBlast
Function
control of ComA activity
Product
phosphatase (RapC) regulator / competence and sporulation stimulating factor (CSF)
Essential
no
E.C.
null
Synonyms
phrC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
429,963 → 430,085
The protein
Catalyzed reaction/ biological activity
binds to RapC, this results in the inability of RapC to interact with ComA PubMed
Protein family
phr family (according to UniProt)
Structure
4GYO (PDB) (complex RapJ-PhrC) PubMed
P94416 (AlphaFold)
Expression and Regulation
Operons
Genes
rapC-phrC
Description
PubMed
Regulation
expressed at high cell density (ComA) PubMed
Regulatory mechanism
CodY: repression, PubMed, in codY regulon
ComA: activation, (ComA) PubMed, in comA regulon
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigH: sigma factor, PubMed, in sigH regulon
Open in new tab

rapC→phrC

2025-04-11 21:34:03

ghost

82

d557cd87272a9075c3ffbe931e4b5edeb40e54a7

4C234676BFA582602106F93B45E171FF3EF2C098

Genes
phrC
Description
PubMed
Regulation
expressed at high cell density (ComA) PubMed
Open in new tab

phrC

2025-04-20 22:52:01

ghost

78

0c4c2871826072f696f4a92077c61b43ea5b999b

8E7ED77CC8409D333846B8D228772A45BC29098C

Biological materials
Mutant
BKE03780 (ΔphrC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACTTAGATTTCAATTTCATA,  downstream forward: _UP4_TAAGAACAAGCCCCTTCTCA
BKK03780 (ΔphrC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACTTAGATTTCAATTTCATA,  downstream forward: _UP4_TAAGAACAAGCCCCTTCTCA
References
Reviews
Loading
Original Publications
Loading

C0B7845F55A16300EB37F026C817AEC4F3BA3B6F

Page visits: 5001

Time of last update: 2025-04-20 21:27:49

Author of last update: Jstuelk