ycbM

ycbM
168

two-component sensor kinase

Locus
BSU_02560
Molecular weight
17.85 kDa
Isoelectric point
9.75
Protein length
311 aaSequenceBlast
Gene length
936 bpSequenceBlast
Function
unknown
Product
two-component sensor kinase
Essential
no
Synonyms
ycbM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2205 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
279,059  279,994
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of YcbL (putative)
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine
Domains
Histidine kinase domain (aa 92-310) (according to UniProt)
Structure
5C93 (PDB) (WalK from Lactobacillus plantarum, 27% identity) PubMed
P42245 (AlphaFold)
Modification
autophosphorylation on a His residue
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
ycbL-ycbM-ycbN-ycbO
Description
PubMed
Open in new tab

ycbL→ycbO

2025-04-03 13:33:42

Jstuelk

80

77090242fa94fd81070f7200512e38f969f10d55

C42DE0C164AE1418C323B42BA4174D5584CA1EA2

Biological materials
Mutant
MGNA-C035 (ycbM::erm), available at the NBRP B. subtilis, Japan
BKE02560 (ycbM::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AGCGGCCACCCATAGCACTG,  downstream forward: _UP4_TAATCGTAAGAATTTCTTAA
BKK02560 (ycbM::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AGCGGCCACCCATAGCACTG,  downstream forward: _UP4_TAATCGTAAGAATTTCTTAA
References
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348F81B6ECB6FFBEC092A672FF5F40FE86918872

Page visits: 2850

Time of last update: 2025-04-10 02:02:13

Author of last update: Melvin.boenninger