Difference between revisions of "NagZ"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01660&redirect=T BSU01660] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01660&redirect=T BSU01660] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3BMX 3BMX] {{PubMed|20826810}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3BMX 3BMX] {{PubMed|20826810}} | ||
Revision as of 12:51, 2 April 2014
- Description: N-acetylglucosaminidase
| Gene name | nagZ |
| Synonyms | yzbA, ybbD |
| Essential | no |
| Product | N-acetylglucosaminidase |
| Function | cell wall recycling |
| Gene expression levels in SubtiExpress: nagZ | |
| Metabolic function and regulation of this protein in SubtiPathways: nagZ | |
| MW, pI | 70 kDa, 9.76 |
| Gene length, protein length | 1926 bp, 642 aa |
| Immediate neighbours | ybbC, amiE |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall degradation/ turnover
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01660
Phenotypes of a mutant
increased autolysis PubMed
Database entries
- BsubCyc: BSU01660
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: cleaves muropeptides derived from peptidoglycan, but not peptidoglycan itself PubMed
- Protein family: glycosyl hydrolase 3 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- secreted (with signal peptide), remains to some extent cell wall-associated PubMed
Database entries
- BsubCyc: BSU01660
- UniProt: P40406
- KEGG entry: [2]
- E.C. number: 3.2.1.52
Additional information
The gene is mis-annotated in KEGG as an ortholog of beta-N-acetylhexosaminidase EC 3.2.1.52. It is marked in MetaCyc as “similar to beta-hexosaminidase”. No EC annotation is available in Swiss-ProtSwiss-Prot.supporting the annotation is available. PubMed
Expression and regulation
- Regulation:
- expressed in late exponential and early stationary phase PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: available in Christoph Mayer's lab PubMed
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional references: PubMed
