Difference between revisions of "FolK"
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00790&redirect=T BSU00790] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pabBAC-sul-folBK-yazB-yacF-lysS.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pabBAC-sul-folBK-yazB-yacF-lysS.html] | ||
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00790&redirect=T BSU00790] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IM6 1IM6] (from ''Escherichia coli'', 47% identity, 61% similarity) {{PubMed|12578370}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IM6 1IM6] (from ''Escherichia coli'', 47% identity, 61% similarity) {{PubMed|12578370}} |
Revision as of 12:47, 2 April 2014
- Description: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
Gene name | folK |
Synonyms | |
Essential | no |
Product | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase |
Function | biosynthesis of folate |
Gene expression levels in SubtiExpress: folK | |
Metabolic function and regulation of this protein in SubtiPathways: folK | |
MW, pI | 18 kDa, 4.531 |
Gene length, protein length | 501 bp, 167 aa |
Immediate neighbours | folB, yazB |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00790
Phenotypes of a mutant
Database entries
- BsubCyc: BSU00790
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate (according to Swiss-Prot)
- Protein family: HPPK family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU00790
- UniProt: P29252
- KEGG entry: [3]
- E.C. number: 2.7.6.3
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References