Difference between revisions of "FolB"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00780&redirect=T BSU00780] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pabBAC-sul-folBK-yazB-yacF-lysS.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pabBAC-sul-folBK-yazB-yacF-lysS.html] | ||
| Line 95: | Line 96: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00780&redirect=T BSU00780] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1U68 1U68] (from ''Staphylococcus aureus'', 47% identity, 72% similarity) {{PubMed|15027862}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1U68 1U68] (from ''Staphylococcus aureus'', 47% identity, 72% similarity) {{PubMed|15027862}} | ||
Revision as of 12:47, 2 April 2014
- Description: dihydroneopterin aldolase
| Gene name | folB |
| Synonyms | folA, yacE |
| Essential | no |
| Product | dihydroneopterin aldolase |
| Function | biosynthesis of folate |
| Gene expression levels in SubtiExpress: folB | |
| Metabolic function and regulation of this protein in SubtiPathways: folB | |
| MW, pI | 13 kDa, 5.228 |
| Gene length, protein length | 360 bp, 120 aa |
| Immediate neighbours | sul, folK |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00780
Phenotypes of a mutant
Database entries
- BsubCyc: BSU00780
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde (according to Swiss-Prot)
- Protein family: DHNA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU00780
- UniProt: P28823
- KEGG entry: [3]
- E.C. number: 4.1.2.25
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Antoine de Saizieu, Pierre Vankan, Cassandra Vockler, Adolphus P G M van Loon
The trp RNA-binding attenuation protein (TRAP) regulates the steady-state levels of transcripts of the Bacillus subtilis folate operon.
Microbiology (Reading): 1997, 143 ( Pt 3);979-989
[PubMed:9084182]
[WorldCat.org]
[DOI]
(P p)
