veg

veg
168

negative effector of SinR activity

Locus
BSU_00440
Molecular weight
9.41 kDa
Isoelectric point
4.81
Protein length
86 aaSequenceBlast
Gene length
261 bpSequenceBlast
Function
control of biofilm formation
Product
negative effector of SinR activity
Essential
no
Synonyms
veg
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG4466 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
52,763 → 53,023
Phenotypes of a mutant
inactivation of the veg gene suppresses the growth defect of a cspB cspD double mutant PubMed
The protein
Catalyzed reaction/ biological activity
overexpression of veg induces expression of the tapA-sipW-tasA operon PubMed
Veg may inhibit the SlrR-SinR interaction PubMed
Structure
3FB9 (PDB) (from Streptococcus pneumoniae, 34% identity)
P37466 (AlphaFold)
Localization
cytoplasm PubMed
Expression and Regulation
Operons
Genes
veg
Description
PubMed
Regulation
constitutively expressed PubMed
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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veg

2025-03-07 20:39:10

ghost

72

6f1bb1005cb5aadaa9b38494716defc645e7e9d2

6DE239061A74A807BB4E807B98D4CDFF544CF7BF

Biological materials
Mutant
GP2888 (Δveg::ermC trpC2) available in Jörg Stülke's lab PubMed
MGNA-B909 (veg::erm), available at the NBRP B. subtilis, Japan
BKE00440 (Δveg::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCATCCACCTCACTAC,  downstream forward: _UP4_TAACGGGCAGTGAACCTTTT
BKK00440 (Δveg::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCATCCACCTCACTAC,  downstream forward: _UP4_TAACGGGCAGTGAACCTTTT
Expression vectors
pGP3138: Constitutive overexpression, based on pBQ200, available in Jörg Stülke's lab
LacZ fusion
GP2898 (amyE::(Pveg-lacZ cat) trpC2) available in Jörg Stülke's lab
References
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Time of last update: 2025-04-05 22:51:42

Author of last update: Jstuelk