Difference between revisions of "Tmk"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00280&redirect=T BSU00280] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00280&redirect=T BSU00280] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CCK 2CCK] (from ''Staphylococcus aureus'', 53% identity, 74% similarity) {{PubMed|16522804}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CCK 2CCK] (from ''Staphylococcus aureus'', 53% identity, 74% similarity) {{PubMed|16522804}} | ||
Revision as of 12:45, 2 April 2014
- Description: thymidylate kinase
| Gene name | tmk |
| Synonyms | yaaP |
| Essential | yes PubMed |
| Product | thymidylate kinase |
| Function | TTP biosynthesis |
| Gene expression levels in SubtiExpress: tmk | |
| Metabolic function and regulation of this protein in SubtiPathways: tmk | |
| MW, pI | 23 kDa, 4.866 |
| Gene length, protein length | 636 bp, 212 aa |
| Immediate neighbours | yaaO, yaaQ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00280
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU00280
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + dTMP = ADP + dTDP (according to Swiss-Prot)
- Protein family: thymidylate kinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU00280
- UniProt: P37537
- KEGG entry: [2]
- E.C. number: 2.7.4.9
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
