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* In a paper from the labs of [[Roberto Kolter]] and [[Richard Losick]] {{PubMed|22541437}} it was reported that ''B. subtilis'' synthesizes norspermidine and that this compound is involved in biofilm disassembly. Now, [http://www.ncbi.nlm.nih.gov/pubmed/24529384 Hobley et al.] from the lab of [[Nicola Stanley-Wall]] provide compelling evidence that ''B. subtilis'' does not produce norspermidine, that previous function annotations of a norspermidine biosynthetic pathway were made in error, and that norspermidine stimulates [[biofilm formation]]. | * In a paper from the labs of [[Roberto Kolter]] and [[Richard Losick]] {{PubMed|22541437}} it was reported that ''B. subtilis'' synthesizes norspermidine and that this compound is involved in biofilm disassembly. Now, [http://www.ncbi.nlm.nih.gov/pubmed/24529384 Hobley et al.] from the lab of [[Nicola Stanley-Wall]] provide compelling evidence that ''B. subtilis'' does not produce norspermidine, that previous function annotations of a norspermidine biosynthetic pathway were made in error, and that norspermidine stimulates [[biofilm formation]]. | ||
| − | * '''Relevant ''Subti''Wiki pages:''' [[ | + | * '''Relevant ''Subti''Wiki pages:''' [[Mark Dillingham]], [[DNA repair/ recombination]], [[AddA]], [[AddB]] |
| − | <pubmed> | + | <pubmed> 24682829 24670664 </pubmed> |
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* [[Previous papers of the month]] | * [[Previous papers of the month]] | ||
Revision as of 10:58, 2 April 2014
Welcome to SubtiWiki! - Bacillus subtilis annotation the "wiki" way!
Contact: General Microbiology, University of Göttingen, send mail
Upcoming events:
- The 6th European Spores Conference will be held in London from April 9 to April 11, 2014. The meeting will be organized by Simon Cutting and Imrich Barak, website, contact
- The next European BACELL meeting will take place in Bratislava from April 29 to April 30, 2014. The meeting will be organized by Imrich Barak, website, contact, program
- PTS 50 - The PTS celebrates 50 years of transport and regulation, organized by Josef Deutscher, Milton Saier and Jörg Stülke will take place from September 07 to 08 in Göttingen, Germany. website, Registration form, contact
- The 1st International Conference on Post-Translational Modifications in Bacteria, organized by Ivan Mijakovic, Christophe Grangeasse, Alan Kent Nielsen and Jörg Stülke will take place from September 09 to 10 in Göttingen, Germany. website, Registration form, contact
- Past conferences
New: Subtiwiki is now on Facebook - please give it a +1!
Now online: A new description of SubtiWiki and its acompanying modules in the 2014 Database issue of Nucleic Acids Research
Paper of the month: April 2014
- In a paper from the labs of Roberto Kolter and Richard Losick PubMed it was reported that B. subtilis synthesizes norspermidine and that this compound is involved in biofilm disassembly. Now, Hobley et al. from the lab of Nicola Stanley-Wall provide compelling evidence that B. subtilis does not produce norspermidine, that previous function annotations of a norspermidine biosynthetic pathway were made in error, and that norspermidine stimulates biofilm formation.
- Relevant SubtiWiki pages: Mark Dillingham, DNA repair/ recombination, AddA, AddB
New procedure for account creation:
- Due to massive spam attacks, we had to change our policy for the creation of accounts. If you want to create an account, just send me a mail. We will create the account for you as quickly as possible, then you can change your password. This does not affect existing accounts, which remain active.
- Please remember that all members of the Bacillus community are invited to create accounts and to contribute to SubtiWiki!
News in SubtiWiki:
- April 2013: SubtiWiki uses a new, faster Mediawiki platform! The times for page access are significantly reduced. Enjoy!
- March 2013: updated Excel files that map all genes to categories and regulons as well as the general updated identity mapping of all genes were uploaded.
- October 2012: the essential genes have been categorized
- September 2012: 300 mutant strains available at the BGSC were added to the corresponding gene pages
- August 2012: SubtiExpress, the new compagnon of SubtiWiki devoted to gene expression is online! Try it out!
- April 2012: Links for expression data under 104 different conditions (based on Nicolas et al., 2012) have been added to the expression section of the individual gene pages
- April 2011: SubtInteract, a presentation of protein-protein interactions in B. subtilis, is online!
- December 2010: SubtiCellPublisher allows the conversion of CellDesigner diagrams to navigatable presentations in the style of SubtiPathways
| Genes (examples) | Additional pages |
| spo0A | SubtiPathways |
| glnA | SubtInteract |
| rny | SubtiExpress |
| psdA | Regulons |
| pckA | methods |
| dnaA | metabolism |
| rnpA | categories |
| sigB | genome-wide analyses |
| ptkA | list of plasmids |
| mreC | labs working on Bacillus |
| ccpA | the people behind SubtiWiki |
| sr1 | template |
Publications describing SubtiWiki and SubtiPathways:
Raphael H Michna, Fabian M Commichau, Dominik Tödter, Christopher P Zschiedrich, Jörg Stülke
SubtiWiki-a database for the model organism Bacillus subtilis that links pathway, interaction and expression information.
Nucleic Acids Res: 2014, 42(Database issue);D692-8
[PubMed:24178028]
[WorldCat.org]
[DOI]
(I p)
Ulrike Mäder, Arne G Schmeisky, Lope A Flórez, Jörg Stülke
SubtiWiki--a comprehensive community resource for the model organism Bacillus subtilis.
Nucleic Acids Res: 2012, 40(Database issue);D1278-87
[PubMed:22096228]
[WorldCat.org]
[DOI]
(I p)
Lope A Flórez, Sebastian F Roppel, Arne G Schmeisky, Christoph R Lammers, Jörg Stülke
A community-curated consensual annotation that is continuously updated: the Bacillus subtilis centred wiki SubtiWiki.
Database (Oxford): 2009, 2009;bap012
[PubMed:20157485]
[WorldCat.org]
[DOI]
(I p)
Christoph R Lammers, Lope A Flórez, Arne G Schmeisky, Sebastian F Roppel, Ulrike Mäder, Leendert Hamoen, Jörg Stülke
Connecting parts with processes: SubtiWiki and SubtiPathways integrate gene and pathway annotation for Bacillus subtilis.
Microbiology (Reading): 2010, 156(Pt 3);849-859
[PubMed:19959575]
[WorldCat.org]
[DOI]
(I p)
