NarK

• Description: nitrite extrusion protein
  
  

Gene name	narK
Synonyms
Essential	no
Product	nitrite extrusion protein
Function	nitrate respiration, nitrite export
Gene expression levels in SubtiExpress: narK
Metabolic function and regulation of this protein in SubtiPathways: narK
MW, pI	42 kDa, 10.099
Gene length, protein length	1185 bp, 395 aa
Immediate neighbours	fnr, argS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, respiration, membrane proteins

This gene is a member of the following regulons

Fnr regulon, NsrR regulon

The gene

Basic information

• Locus tag: BSU37320

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): NasA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: P46907

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: narK-fnr PubMed

• Expression browser: narK PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • expressed under anaerobic conditions (Fnr) PubMed
  • induced by nitric oxide under anaerobic conditions (NsrR) PubMed

• Regulatory mechanism:
  • NsrR: transcription repression PubMed
  • Fnr: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

D J Richardson, B C Berks, D A Russell, S Spiro, C J Taylor
Functional, biochemical and genetic diversity of prokaryotic nitrate reductases.
Cell Mol Life Sci: 2001, 58(2);165-78
[PubMed:11289299] [WorldCat.org] [DOI] (P p)