Difference between revisions of "YwaA"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
− | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}} | + | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, |
+ | [[most abundant proteins]] | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
Line 117: | Line 118: | ||
* '''Additional information:''' | * '''Additional information:''' | ||
+ | ** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}} | ||
=Biological materials = | =Biological materials = | ||
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=References= | =References= | ||
− | <pubmed>12670965,17611193,24163341, </pubmed> | + | <pubmed>12670965,17611193,24163341, 15378759</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 16:16, 5 March 2014
- Description: branched-chain amino acid aminotransferase
Gene name | ywaA |
Synonyms | ipa-0r |
Essential | no |
Product | branched-chain amino acid aminotransferase |
Function | biosynthesis of branched-chain amino acids |
Gene expression levels in SubtiExpress: ywaA | |
Metabolic function and regulation of this protein in SubtiPathways: ywaA | |
MW, pI | 40 kDa, 4.952 |
Gene length, protein length | 1089 bp, 363 aa |
Immediate neighbours | dltE, licH |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38550
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate (according to Swiss-Prot)
- Protein family: class-IV pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
- Paralogous protein(s): YbgE
Extended information on the protein
- Kinetic information:
- Modification: S-cysteinylation after diamide stress (C104) PubMed
- Effectors of protein activity:
Database entries
- UniProt: P39576
- KEGG entry: [3]
- E.C. number: 2.6.1.42
Additional information
Expression and regulation
- Operon: ywaA PubMed
- Additional information:
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- a ywaA::spc mutant and a bcd ybgE ywaA triple mutant are available in Linc Sonenshein's lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References