Difference between revisions of "ScpB"
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| − | * '''Description:''' | + | * '''Description:''' part of the [[condensin]] complex, chromosomal origin condensation and segregation <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || DNA segregation and condensation protein | |style="background:#ABCDEF;" align="center"| '''Product''' || DNA segregation and condensation protein | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || segregation of replication origins |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23210 scpB] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23210 scpB] | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | * | + | * ''[[scpB]]'' mutants are not viable on complex medim that allow rapid growth, but they are viable under conditions of slow growth {{PubMed|24440399,24440393}} |
=== Database entries === | === Database entries === | ||
| Line 76: | Line 76: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** part of the [[condensin]] complex {{PubMed|24440399,24440393}} | ||
** forms dimers {{PubMed|22385855}} | ** forms dimers {{PubMed|22385855}} | ||
** [[ScpB]]-[[Smc]] {{PubMed|22385855,12100548}}, this interaction takes place only in the presence of [[ScpA]] {{PubMed|22385855}} | ** [[ScpB]]-[[Smc]] {{PubMed|22385855,12100548}}, this interaction takes place only in the presence of [[ScpA]] {{PubMed|22385855}} | ||
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
** nucleoid (Multiple) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] | ** nucleoid (Multiple) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] | ||
| − | ** the ([[Smc]])2-[[ScpA]]-[[ScpB]] complex forms two bipolar assemblies on the chromosome, one in each cell half {{PubMed|23475963}} | + | ** the [[condensin]] ([[Smc]])2-[[ScpA]]-[[ScpB]] complex forms two bipolar assemblies on the chromosome, one in each cell half, localization depends on [[Spo0J]] {{PubMed|24440393,23475963}} |
=== Database entries === | === Database entries === | ||
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<pubmed> 22933559 22934648 </pubmed> | <pubmed> 22933559 22934648 </pubmed> | ||
== Original publications == | == Original publications == | ||
| − | <pubmed>12100548,12065423,12421306,22385855, 16479537, 19450516 12897137 7934830 11948165 23353789 24440393 | + | <pubmed>12100548,12065423,12421306,22385855, 16479537, 19450516 12897137 7934830 11948165 23353789 24440399,24440393 23475963</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:28, 16 February 2014
- Description: part of the condensin complex, chromosomal origin condensation and segregation
| Gene name | scpB |
| Synonyms | ypuH |
| Essential | no |
| Product | DNA segregation and condensation protein |
| Function | segregation of replication origins |
| Gene expression levels in SubtiExpress: scpB | |
| Interactions involving this protein in SubtInteract: ScpB | |
| MW, pI | 21 kDa, 4.25 |
| Gene length, protein length | 591 bp, 197 aa |
| Immediate neighbours | ypuI, scpA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23210
Phenotypes of a mutant
- scpB mutants are not viable on complex medim that allow rapid growth, but they are viable under conditions of slow growth PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: scpB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- UniProt: P35155
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
