Difference between revisions of "YfmR"

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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
** a paraloguous protein from ''E. coli''  (EttA) gates [[ribosome]] entry into the translation elongation cycle {{PubMed|24389466}}
+
** a paraloguous protein from ''E. coli''  (EttA) gates [[ribosome]] entry into the translation elongation cycle {{PubMed|24389465,24389466}}
 
* '''Protein family:'''
 
* '''Protein family:'''
  
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=References=
 
=References=
  
<pubmed>10092453, 24389466, </pubmed>
+
<pubmed>10092453, 24389466, 24389465 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 13:48, 8 January 2014

Gene name yfmR
Synonyms
Essential no
Product ABC transporter (ATP-binding protein)
Function unknown
Gene expression levels in SubtiExpress: yfmR
MW, pI 70 kDa, 4.997
Gene length, protein length 1887 bp, 629 aa
Immediate neighbours yfmS, yfmQ
Sequences Protein DNA DNA_with_flanks
Genetic context
YfmR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YfmR expression.png















Categories containing this gene/protein

ABC transporters

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU07370

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • a paraloguous protein from E. coli (EttA) gates ribosome entry into the translation elongation cycle PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Grégory Boël, Paul C Smith, Wei Ning, Michael T Englander, Bo Chen, Yaser Hashem, Anthony J Testa, Jeffrey J Fischer, Hans-Joachim Wieden, Joachim Frank, Ruben L Gonzalez, John F Hunt
The ABC-F protein EttA gates ribosome entry into the translation elongation cycle.
Nat Struct Mol Biol: 2014, 21(2);143-51
[PubMed:24389466] [WorldCat.org] [DOI] (I p)

Bo Chen, Grégory Boël, Yaser Hashem, Wei Ning, Jingyi Fei, Chi Wang, Ruben L Gonzalez, John F Hunt, Joachim Frank
EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics.
Nat Struct Mol Biol: 2014, 21(2);152-9
[PubMed:24389465] [WorldCat.org] [DOI] (I p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)