Difference between revisions of "DsdA"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23770 dsdA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23770 dsdA]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/CoA_synthesis.html Coenzyme A]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=dsdA dsdA]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 5.55   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 5.55   

Revision as of 11:09, 7 January 2014

  • Description: D-serine deaminase

Gene name dsdA
Synonyms yqjR
Essential no
Product D-serine deaminase
Function unknown
Gene expression levels in SubtiExpress: dsdA
Metabolic function and regulation of this protein in SubtiPathways:
dsdA
MW, pI 49 kDa, 5.55
Gene length, protein length 1344 bp, 448 aa
Immediate neighbours coaA, yqjQ
Sequences Protein DNA DNA_with_flanks
Genetic context
DsdA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DsdA expression.png




























Categories containing this gene/protein

poorly characterized/ putative enzymes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU23770

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-serine = pyruvate + NH3 (according to Swiss-Prot)
  • Protein family: DsdA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

C Parsot
Evolution of biosynthetic pathways: a common ancestor for threonine synthase, threonine dehydratase and D-serine dehydratase.
EMBO J: 1986, 5(11);3013-9
[PubMed:3098560] [WorldCat.org] [DOI] (P p)