Difference between revisions of "MrpA"
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | * essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | |
| − | essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | + | * a ''[[mrpA]]'' mutant is viable at pH7.4 and sodium concentrations below 80 mM {{PubMed|24139955}} |
| + | * the ''[[mrpA]]'' mutant accumulates internal sodium {{PubMed|24139955}} | ||
=== Database entries === | === Database entries === | ||
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=== Additional information=== | === Additional information=== | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
Revision as of 15:27, 22 December 2013
- Description: Na+ transporter subunit of the Na+/H+ antiporter, multiple resistance and pH homeostasis
| Gene name | mrpA |
| Synonyms | yufT, shaA, ntrA |
| Essential | yes PubMed |
| Product | Na+/H+ antiporter subunit |
| Function | sodium export |
| Gene expression levels in SubtiExpress: mrpA | |
| Interactions involving this protein in SubtInteract: MrpA | |
| MW, pI | 86 kDa, 9.519 |
| Gene length, protein length | 2322 bp, 774 aa |
| Immediate neighbours | yufS, mrpB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31600
Phenotypes of a mutant
- essential PubMed
- a mrpA mutant is viable at pH7.4 and sodium concentrations below 80 mM PubMed
- the mrpA mutant accumulates internal sodium PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Na+ transporter subunit of the Na+/H+ antiporter PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: Q9K2S2
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
