Difference between revisions of "PksA"

From SubtiWiki
Jump to: navigation, search
Line 1: Line 1:
* '''Description:''' transcriptional regulator ([[TetR family]]) of the polyketide synthase operon <br/><br/>
+
* '''Description:''' transcriptional regulator ([[TetR family]]), '''not''' involved in the regulation of the ''pks'' operon! <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 12: Line 12:
 
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator ([[TetR family]])
 
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator ([[TetR family]])
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of polyketide synthesis
+
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17080 pksA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17080 pksA]
Line 38: Line 38:
  
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[miscellaneous metabolic pathways]]}},
+
{{SubtiWiki category|[[transcription factors and their control]]}}
{{SubtiWiki category|[[transcription factors and their control]]}},
 
{{SubtiWiki category|[[biosynthesis of antibacterial compounds]]}}
 
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
Line 138: Line 136:
 
<pubmed>24006471 </pubmed>
 
<pubmed>24006471 </pubmed>
 
==Original publications==
 
==Original publications==
 +
<pubmed>24187085 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 13:09, 17 December 2013

  • Description: transcriptional regulator (TetR family), not involved in the regulation of the pks operon!

Gene name pksA
Synonyms
Essential no
Product transcriptional regulator (TetR family)
Function unknown
Gene expression levels in SubtiExpress: pksA
MW, pI 23 kDa, 6.436
Gene length, protein length 615 bp, 205 aa
Immediate neighbours ymcC, pksB
Sequences Protein DNA DNA_with_flanks
Genetic context
PksA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PksA expression.png















Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17080

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Leslie Cuthbertson, Justin R Nodwell
The TetR family of regulators.
Microbiol Mol Biol Rev: 2013, 77(3);440-75
[PubMed:24006471] [WorldCat.org] [DOI] (I p)

Original publications

Carol Vargas-Bautista, Kathryn Rahlwes, Paul Straight
Bacterial competition reveals differential regulation of the pks genes by Bacillus subtilis.
J Bacteriol: 2014, 196(4);717-28
[PubMed:24187085] [WorldCat.org] [DOI] (I p)