Difference between revisions of "ComP"

From SubtiWiki
Jump to: navigation, search
Line 39: Line 39:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
+
<br/><br/>
<br/><br/><br/><br/>
 
 
 
 
 
<br/><br/><br/><br/>
 
  
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
Line 63: Line 59:
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* the mutation suppresses the mucoid phenotype of ''[[motA]]'' or ''[[motB]]'' mutants due to loss of [[DegU]] phosphorylation and concomitant reduced expression of the ''[[pgsB]]-[[pgsC]]-[[pgsA]]'' operon {{PubMed|24296669}}
  
 
=== Database entries ===
 
=== Database entries ===
Line 71: Line 68:
  
 
=== Additional information===
 
=== Additional information===
 
 
  
  
Line 89: Line 84:
 
* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:''' eight transmembrane segments
+
* '''[[Domains]]:''' eight transmembrane segments
  
 
* '''Modification:''' autophosphorylation on a His residue
 
* '''Modification:''' autophosphorylation on a His residue
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:''' [[ComX]] (extracellular)
 
* '''Effectors of protein activity:''' [[ComX]] (extracellular)
Line 120: Line 115:
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comP_3253529_3255838_-1 comP] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comP_3253529_3255838_-1 comP] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 150: Line 145:
 
<pubmed>12576575 </pubmed>
 
<pubmed>12576575 </pubmed>
 
==Original Publications==
 
==Original Publications==
<pubmed>11133937,8643670,12067344,10094672,10419951,2116363,9274030 18763711 </pubmed>
+
<pubmed>11133937,8643670,12067344,10094672,10419951,2116363,9274030 18763711 24296669 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:05, 4 December 2013

Gene name comP
Synonyms
Essential no
Product two-component sensor kinase
Function regulation of genetic competence and quorum sensing
Gene expression levels in SubtiExpress: comP
Interactions involving this protein in SubtInteract: ComP
MW, pI 89 kDa, 7.997
Gene length, protein length 2307 bp, 769 aa
Immediate neighbours comA, comX
Sequences Protein DNA DNA_with_flanks
Genetic context
ComP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComP expression.png















Categories containing this gene/protein

genetic competence, protein modification, transcription factors and their control, quorum sensing, membrane proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU31690

Phenotypes of a mutant

  • the mutation suppresses the mucoid phenotype of motA or motB mutants due to loss of DegU phosphorylation and concomitant reduced expression of the pgsB-pgsC-pgsA operon PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of ComA
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: eight transmembrane segments
  • Modification: autophosphorylation on a His residue
  • Effectors of protein activity: ComX (extracellular)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications